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TACROLIMUS BINDING PROTEIN 1A
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DeCS
Descriptor
English
:
Tacrolimus Binding Protein 1A
Descriptor
Spanish
:
Proteína 1A de Unión a Tacrolimus
Descriptor
Portuguese
:
Proteína 1A de Ligação a Tacrolimo
Synonyms
English
:
FK506-Binding Protein 1A
FKBP12
Tree Number:
D08.811.399.325.500.400.700.500
D12.776.543.750.705.400.700.500
D12.776.827.275.700.500
Definition
English
:
A 12-KDa
tacrolimus
binding protein that is found associated with and may modulate the function of
calcium
release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both
tacrolimus
(commonly called FK506) and
SIROLIMUS.
History Note
English
:
2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
35327
Unique Identifier:
D022061
Occurrence in VHL
:
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